Post Doctoral Fellow, Computational Biology/Oncology, Assaf Lab (roche)

Job Description

We are seeking a talented and highly motivated Postdoctoral Fellow to become part of our dynamic team in the Computational Sciences Department (gCS) within Genentech's Research & Development division (gRED). The successful candidate will work in a highly interdisciplinary environment at the intersection of the Computational Biology, Translational Medicine and Technology Innovation groups to study cancer biology using deep clinicogenomics data and cutting edge NGS diagnostics. 

The Opportunity:

• Opportunity to drive scientific, analytic, and technical innovation in a community of scientific experts in oncology research and computational biology. 

• Dive into clinical and genomics data from 1000’s of patients to interrogate tumor biology, discover novel targets and biomarkers, and accelerate translational research.

• Build or leverage novel artificial intelligence and machine learning (AI/ML) techniques for advanced liquid biopsy (ctDNA) and tissue transcriptomic (RNA-seq) data to predict patient tumor biology from a simple blood draw. 

• Present at external scientific conferences and publish scientific insights from this research in high impact journals. 

Who You Are / Required Qualifications:

• Ph.D. in Computational Biology, Bioinformatics, Computer Science or related field.

• Demonstrated proficiency in Python or R, with experience building bioinformatic workflows and documenting code with version control. 

• Proficiency in genomics data analysis, preferably including two or more of the following: 

  • Epigenetic data (methylation, 5hmc, etc)

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  • Chromatin accessibility data (ATAC-seq, fragmentomics, etc.)

  • Transcriptomics data (single cell or bulk RNA-seq)

  • Whole genome (WGS), whole exome (WES), or other DNA sequence data 

  • Liquid biopsy or ctDNA data

• Experience applying AI/ML to problems in computational biology, such as building or using AI/ML workflows, frameworks, or libraries in combination with genomics datasets. 

• Excellent communication skills, able to present complex data to varied audiences.

• Highly independent and a quick learner, eager to learn new areas and build expertise.

Preferred Qualifications:

• Practical experience or familiarity with self-supervised learning, representation learning, foundation models, or related machine learning approaches.

• Background in cancer biology, cancer genomics, or clinical data analysis in oncology

• Preferably a strong publication record or impactful first author paper. 

• Familiarity working with publicly available genomics data and working in  high-performance computing (HPC) and/or UNIX environments is a plus. 

• Highly motivated, able to creatively take initiative to see your ideas implemented and your vision executed, while maintaining a collaborative mindset.

The expected salary range for this position based on the primary location of California is $110,000 to $120,000.. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are available for this job posting.

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About Genentech’s Postdoctoral Program:

Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.

The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader. The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech’s Postdoctoral Program and unlock your full potential!

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.